How alum works

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How alum works

For more than 70 years, alum has been used as a trusty aide to improve antibody responses to vaccines. But how this aluminum-containing compound boosts the response to vaccines has been a mystery. On page 869, Kool et al. expose its mysterious mechanism; they find that alum causes cells to produce a stim-ulator of dendritic cells (DCs). DCs were once the favored hypothetical link between alum a...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 2008

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.2054iti1